Wolfgang Baehr Selected Research

Retinaldehyde (Retinal)

1/2016	Ciliopathy-associated protein CEP290 modifies the severity of retinal degeneration due to loss of RPGR.
6/2013	Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.
1/2012	Retinoid receptors trigger neuritogenesis in retinal degenerations.
10/2011	Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function.
5/2011	Cone opsin determines the time course of cone photoreceptor degeneration in Leber congenital amaurosis.
6/2008	Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.
4/2008	Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
11/2005	Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.
9/2003	Retinal remodeling triggered by photoreceptor degenerations.

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Wolfgang Baehr Research Topics

Disease

7	Leber Congenital Amaurosis 03/2014 - 04/2008
6	Retinal Degeneration 01/2016 - 09/2003
5	Blue cone monochromatism 10/2021 - 01/2017
5	Ciliopathies 01/2021 - 01/2014
4	Retinitis Pigmentosa (Pigmentary Retinopathy) 10/2021 - 01/2004
4	Cone-Rod Dystrophies 11/2018 - 01/2005
4	Blindness (Hysterical Blindness) 01/2016 - 11/2005
3	Agenesis of Cerebellar Vermis 01/2021 - 01/2014
3	Macular Degeneration (Age-Related Maculopathy) 06/2013 - 10/2004
2	Color Vision Defects (Color Blindness) 10/2021 - 03/2014
2	Cone Dystrophy 10/2021 - 07/2003
2	Retinal Dystrophies 01/2014 - 05/2011
1	Atrophy 11/2018
1	Hyperpigmentation 11/2018
1	Retinitis Pigmentosa 2 03/2015
1	Coloboma of optic nerve 01/2014
1	Intellectual Disability (Idiocy) 01/2014
1	Obesity 01/2014
1	Penis agenesis 01/2014
1	Polydactyly (Polydactylism) 01/2014
1	Choroidal Neovascularization 06/2013
1	Photophobia (Light Sensitivity) 05/2013
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2012
1	Gliosis 10/2011
1	Liver Cirrhosis (Hepatic Cirrhosis) 10/2005
1	Disease Progression 10/2004
1	Early Onset Severe Retinal Dystrophy 03/2004
1	Hypertrophy 09/2003

Drug/Important Bio-Agent (IBA)

9	Retinaldehyde (Retinal)IBA 01/2016 - 09/2003
6	Proteins (Proteins, Gene)FDA Link 10/2016 - 03/2010
4	Cone OpsinsIBA 10/2021 - 06/2008
3	GTP Phosphohydrolases (GTPases)IBA 01/2016 - 01/2004
3	RetinoidsIBA 01/2012 - 12/2007
2	Rhodopsin (Visual Purple)IBA 10/2021 - 09/2003
2	OpsinsIBA 01/2019 - 01/2018
2	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 03/2015 - 12/2014
2	Monomeric GTP-Binding ProteinsIBA 03/2015 - 01/2004
2	Guanylate Cyclase (Guanylyl Cyclase)IBA 03/2014 - 02/2013
2	retinoid isomerohydrolase (retinol isomerase)IBA 03/2014 - 06/2012
2	lecithin-retinol acyltransferaseIBA 06/2012 - 05/2011
2	Retinyl EstersIBA 10/2005 - 03/2004
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021
1	Nonsense Codon (Nonsense Mutation)IBA 11/2018
1	Peptides (Polypeptides)IBA 03/2015
1	phosphatidylinositol 3,4,5-triphosphateIBA 12/2014
1	Guanosine Triphosphate (GTP)IBA 12/2014
1	G-Protein-Coupled Receptor Kinase 1 (G Protein-Coupled Receptor Kinase 1)IBA 12/2014
1	Thyroid HormonesIBA 03/2014
1	Cyclic Nucleotide-Gated Cation ChannelsIBA 03/2014
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 03/2014
1	Carrier Proteins (Binding Protein)IBA 01/2014
1	prenylIBA 01/2014
1	antineoplaston A10 (A 10)IBA 05/2013
1	Guanylate Cyclase-Activating ProteinsIBA 01/2013
1	ursodoxicoltaurineIBA 06/2012
1	Retinoid X Receptors (Retinoid X Receptor)IBA 01/2012
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 10/2011
1	aryl hydrocarbon receptor-interacting proteinIBA 03/2010
1	AC133 AntigenIBA 08/2008
1	Retinal Pigments (Pigments, Visual)IBA 04/2008
1	retinylamineIBA 12/2007
1	A2-E (N-retinylidene-N-retinylethanolamine)IBA 12/2007
1	Carbonic Anhydrase IVIBA 01/2005
1	SymportersIBA 01/2005
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2005
1	Advanced Glycation End ProductsIBA 10/2004
1	Receptor for Advanced Glycation End ProductsIBA 10/2004
1	ArrestinIBA 07/2003

Therapy/Procedure

3	Therapeutics 10/2021 - 01/2017
1	RNAi Therapeutics 01/2014